emg recording electrodes Search Results


surface emg recording electrodes meditrace pellet ag/agcl discs and in diameter  (Graphic Controls Inc)
90
Graphic Controls Inc surface emg recording electrodes meditrace pellet ag/agcl discs and in diameter
Surface Emg Recording Electrodes Meditrace Pellet Ag/Agcl Discs And In Diameter, supplied by Graphic Controls Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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surface emg recording electrodes meditrace pellet ag/agcl discs and in diameter - by Bioz Stars, 2026-09
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eeg/emg recording electrodes  (CMA Microdialysis)
90
CMA Microdialysis eeg/emg recording electrodes
Eeg/Emg Recording Electrodes, supplied by CMA Microdialysis, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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electromyographic (emg) recordings of the right orbicularis occuli muscle using two biosemi flat electrodes  (BioSemi)
90
BioSemi electromyographic (emg) recordings of the right orbicularis occuli muscle using two biosemi flat electrodes
Electromyographic (Emg) Recordings Of The Right Orbicularis Occuli Muscle Using Two Biosemi Flat Electrodes, supplied by BioSemi, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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electromyographic (emg) recordings of the right orbicularis occuli muscle using two biosemi flat electrodes - by Bioz Stars, 2026-09
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fine-wire emg electrodes  (BIOPAC)
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BIOPAC fine-wire emg electrodes
Fine Wire Emg Electrodes, supplied by BIOPAC, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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fine-wire emg electrodes - by Bioz Stars, 2026-09
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27-gauge, 25-mm single fiber emg needle electrode with a platinum-iridium recording surface  (Technomed GmbH)
90
Technomed GmbH 27-gauge, 25-mm single fiber emg needle electrode with a platinum-iridium recording surface
27 Gauge, 25 Mm Single Fiber Emg Needle Electrode With A Platinum Iridium Recording Surface, supplied by Technomed GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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27-gauge, 25-mm single fiber emg needle electrode with a platinum-iridium recording surface - by Bioz Stars, 2026-09
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six emg recording electrodes  (Digi Key Electronics)
90
Digi Key Electronics six emg recording electrodes
A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. <t>EMG</t> <t>electrodes</t> were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.
Six Emg Recording Electrodes, supplied by Digi Key Electronics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/emg+recording+electrodes/six+emg+recording+electrodes/bio_rxiv__2022__05__21__492933-429-6-18
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six emg recording electrodes - by Bioz Stars, 2026-09
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emg recording electrodes  (Digi Key Electronics)
90
Digi Key Electronics emg recording electrodes
A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. <t>EMG</t> <t>electrodes</t> were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.
Emg Recording Electrodes, supplied by Digi Key Electronics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/emg+recording+electrodes/emg+recording+electrodes/pm30303749-56-8-22
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emg recording electrodes - by Bioz Stars, 2026-09
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hd-emg recording electrodes  (FormFactor Inc)
90
FormFactor Inc hd-emg recording electrodes
A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. <t>EMG</t> <t>electrodes</t> were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.
Hd Emg Recording Electrodes, supplied by FormFactor Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/emg+recording+electrodes/hd+emg+recording+electrodes/pm39008975-379-5-12
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hd-emg recording electrodes - by Bioz Stars, 2026-09
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surface emg recording miniature-sized skin electrodes ecg-medola  (Oriola Corporation)
90
Oriola Corporation surface emg recording miniature-sized skin electrodes ecg-medola
A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. <t>EMG</t> <t>electrodes</t> were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.
Surface Emg Recording Miniature Sized Skin Electrodes Ecg Medola, supplied by Oriola Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
surface emg recording miniature-sized skin electrodes ecg-medola - by Bioz Stars, 2026-09
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pre-gelled, self-adhesive surface emg recording electrodes  (Medicotest Inc)
90
Medicotest Inc pre-gelled, self-adhesive surface emg recording electrodes
A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. <t>EMG</t> <t>electrodes</t> were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.
Pre Gelled, Self Adhesive Surface Emg Recording Electrodes, supplied by Medicotest Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/emg+recording+electrodes/pre+gelled++self+adhesive+surface+emg+recording+electrodes/10__1016_slash_j__ergon__2006__04__003-92-4-11
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pre-gelled, self-adhesive surface emg recording electrodes - by Bioz Stars, 2026-09
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emg electrodes hellige ag/agcl surface electrodes with diameter of recording surface  (Hellige GMBH)
90
Hellige GMBH emg electrodes hellige ag/agcl surface electrodes with diameter of recording surface
A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. <t>EMG</t> <t>electrodes</t> were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.
Emg Electrodes Hellige Ag/Agcl Surface Electrodes With Diameter Of Recording Surface, supplied by Hellige GMBH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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emg electrodes hellige ag/agcl surface electrodes with diameter of recording surface - by Bioz Stars, 2026-09
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pre-gelled, self-adhesive surface emg recording electrodes blue sensor  (Medicotest Inc)
90
Medicotest Inc pre-gelled, self-adhesive surface emg recording electrodes blue sensor
A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. <t>EMG</t> <t>electrodes</t> were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.
Pre Gelled, Self Adhesive Surface Emg Recording Electrodes Blue Sensor, supplied by Medicotest Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Average 90 stars, based on 1 article reviews
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Image Search Results


A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. EMG electrodes were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.

Journal: bioRxiv

Article Title: Inhibitory interneurons within the deep dorsal horn integrate convergent sensory input to regulate motor performance

doi: 10.1101/2022.05.21.492933

Figure Lengend Snippet: A) Diagram depicting the 1-nerve stimulation assay designed to reveal the contribution of dPVs to motor activity evoked by stimulation of ipsilateral cutaneous nerves. Nerve cuffs were implanted on the right sural nerve and left saphenous nerve. EMG electrodes were implanted into the right and left semitendinosus (St, knee flexor), right vastus lateralis (VL, knee extensor), left tibialis anterior (TA, ankle flexor) and right and left gastrocnemius (Gs, ankle extensor). EMG responses were recorded from hindlimb flexors and extensors following stimulation of cutaneous nerves (saphenous / sural nerve). B) Example St EMG responses to stimulation of the right saphenous nerve at 5 times threshold (see methods) in dPV norm (top) and dPV abl (bottom), during the experiment described in D. C) Latency to response to stimulation of the saphenous (left) or sural (right) nerves of ipsilateral hindlimb muscles during the experiment depicted in D. D) Top-diagram of the 2-nerve stimulation assay applied to reveal if dPVs mediate sensory-evoked ipsilateral inhibition. Bottom-experiment timeline. Nerve cuffs and EMG electrodes were placed as in D. Stimulation of the contralateral cutaneous nerve (saphenous/ sural) alone (black lightning) was used to calculate the expected response in the absence of sensory evoked ipsilateral inhibition. Following, both nerves were stimulated (yellow lightning), with variable delays and compared to the expected response to reveal ipsilateral inhibition. E) Top-expected Gs EMG response to stimulation of a single cutaneous nerve in dPV abl (left) and dPV norm (right), averaged over 20 responses. Bottom-expected responses (black) superimposed on single trial responses to stimulation of both cutaneous nerves (yellow). Left-response to stimulation of both nerves (15 ms delay), shows a “dip” that is absent in the expected response, indicating ipsilateral inhibition. Right-no “dip” is seen (0 ms delay), suggesting a loss of inhibition. For each mouse and each muscle, the delay in which responses were best aligned was chosen for further analysis. F) Percent inhibition (the percentage of trials where inhibition was detected) in hindlimb muscles, mediated by ipsilateral saphenous (left) and ipsilateral sural (right) nerves, following the experiment in G. Statistical analysis was done using Mann Withney test, with *p < 0.05 and **p < 0.005. Graphs show average +S.E.M. blue and red denote dPV norm and dPV abl , respectively.

Article Snippet: Two nerve cuff electrodes and six EMG recording electrodes were attached to the headpiece pin connector (female, SAM1153-12; DigiKey Electronics Thief River Falls, MN) and covered with 3D printed cap.

Techniques: Activity Assay, Inhibition